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CD14 and Complement Crosstalk and Largely Mediate the Transcriptional Response to Escherichia coli in Human Whole Blood as Revealed by DNA Microarray

Systemic inflammation like in sepsis is still lacking specific diagnostic markers and effective therapeutics. The first line of defense against intruding pathogens and endogenous damage signals is pattern recognition by e.g., complement and Toll-like receptors (TLR). Combined inhibition of a key com...

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Detalles Bibliográficos
Autores principales:	Lau, Corinna, Nygård, Ståle, Fure, Hilde, Olstad, Ole Kristoffer, Holden, Marit, Lappegård, Knut Tore, Brekke, Ole-Lars, Espevik, Terje, Hovig, Eivind, Mollnes, Tom Eirik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338229/ https://www.ncbi.nlm.nih.gov/pubmed/25706641 http://dx.doi.org/10.1371/journal.pone.0117261

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