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Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws

INTRODUCTION: There is a high incidence of vertebral burst fractures following low velocity trauma in the elderly. Treatment of unstable vertebral burst fractures using the same principles like in stable vertebral burst fractures may show less favourable results in terms of fracture reduction, maint...

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Autores principales: Eschler, Anica, Ender, Stephan Albrecht, Schiml, Katharina, Mittlmeier, Thomas, Gradl, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338244/
https://www.ncbi.nlm.nih.gov/pubmed/25706642
http://dx.doi.org/10.1371/journal.pone.0117122
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author Eschler, Anica
Ender, Stephan Albrecht
Schiml, Katharina
Mittlmeier, Thomas
Gradl, Georg
author_facet Eschler, Anica
Ender, Stephan Albrecht
Schiml, Katharina
Mittlmeier, Thomas
Gradl, Georg
author_sort Eschler, Anica
collection PubMed
description INTRODUCTION: There is a high incidence of vertebral burst fractures following low velocity trauma in the elderly. Treatment of unstable vertebral burst fractures using the same principles like in stable vertebral burst fractures may show less favourable results in terms of fracture reduction, maintenance of reduction and cement leakage. In order to address these shortcomings this study introduces cementless fixation of unstable vertebral burst fractures using internal fixators and expandable intravertebral titanium mesh cages in a one-stage procedure via minimum-invasive techniques. MATERIAL AND METHODS: A total of 16 consecutive patients (median age 76 years, range 58–94) with unstable thoracolumbar burst fractures and concomitant osteoporosis were treated by an internal fixator inserted via minimum invasive technique one level above and below the fractured vertebra. Fracture reduction was achieved and maintained by transpedicular placement of two titanium mesh cages into the fractured vertebral body during the same procedure. Intra- and postoperative safety of the procedure as well as analysis of reduction quality was analysed by 3D C-arm imaging or CT, respectively. Clinical and radiographic follow-up averaged 10.4 months (range 4.5–24.5). RESULTS: Stabilization of the collapsed vertebral body was achieved in all 16 cases without any intraoperative complication. Surgical time averaged 102±6.6 minutes (71–194). The postoperative kyphotic angle (KA) and Cobb angle revealed significant improvements (KA 13.7° to 7.4°, p<0.001; Cobb 9.6° to 6.0°, p<0.002) with partial loss of reduction at final follow-up (KA 8.3°, Cobb 8.7°). VAS (Visual Analogue Scale) improved from 7.6 to 2.6 (p<0.001). Adjacent fractures were not observed. One minor (malposition of pedicle screw) complication was encountered. CONCLUSION: Cementless fixation of osteoporotic burst fractures revealed substantial pain relief, adequate maintenance of reduction and a low complication rate. Bony healing after unstable osteoporotic burst fractures is possible. TRIAL REGISTRATION: www.germanctr.de DRKS00005657
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spelling pubmed-43382442015-03-04 Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws Eschler, Anica Ender, Stephan Albrecht Schiml, Katharina Mittlmeier, Thomas Gradl, Georg PLoS One Research Article INTRODUCTION: There is a high incidence of vertebral burst fractures following low velocity trauma in the elderly. Treatment of unstable vertebral burst fractures using the same principles like in stable vertebral burst fractures may show less favourable results in terms of fracture reduction, maintenance of reduction and cement leakage. In order to address these shortcomings this study introduces cementless fixation of unstable vertebral burst fractures using internal fixators and expandable intravertebral titanium mesh cages in a one-stage procedure via minimum-invasive techniques. MATERIAL AND METHODS: A total of 16 consecutive patients (median age 76 years, range 58–94) with unstable thoracolumbar burst fractures and concomitant osteoporosis were treated by an internal fixator inserted via minimum invasive technique one level above and below the fractured vertebra. Fracture reduction was achieved and maintained by transpedicular placement of two titanium mesh cages into the fractured vertebral body during the same procedure. Intra- and postoperative safety of the procedure as well as analysis of reduction quality was analysed by 3D C-arm imaging or CT, respectively. Clinical and radiographic follow-up averaged 10.4 months (range 4.5–24.5). RESULTS: Stabilization of the collapsed vertebral body was achieved in all 16 cases without any intraoperative complication. Surgical time averaged 102±6.6 minutes (71–194). The postoperative kyphotic angle (KA) and Cobb angle revealed significant improvements (KA 13.7° to 7.4°, p<0.001; Cobb 9.6° to 6.0°, p<0.002) with partial loss of reduction at final follow-up (KA 8.3°, Cobb 8.7°). VAS (Visual Analogue Scale) improved from 7.6 to 2.6 (p<0.001). Adjacent fractures were not observed. One minor (malposition of pedicle screw) complication was encountered. CONCLUSION: Cementless fixation of osteoporotic burst fractures revealed substantial pain relief, adequate maintenance of reduction and a low complication rate. Bony healing after unstable osteoporotic burst fractures is possible. TRIAL REGISTRATION: www.germanctr.de DRKS00005657 Public Library of Science 2015-02-23 /pmc/articles/PMC4338244/ /pubmed/25706642 http://dx.doi.org/10.1371/journal.pone.0117122 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
spellingShingle Research Article
Eschler, Anica
Ender, Stephan Albrecht
Schiml, Katharina
Mittlmeier, Thomas
Gradl, Georg
Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws
title Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws
title_full Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws
title_fullStr Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws
title_full_unstemmed Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws
title_short Bony Healing of Unstable Thoracolumbar Burst Fractures in the Elderly Using Percutaneously Applied Titanium Mesh Cages and a Transpedicular Fixation System with Expandable Screws
title_sort bony healing of unstable thoracolumbar burst fractures in the elderly using percutaneously applied titanium mesh cages and a transpedicular fixation system with expandable screws
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338244/
https://www.ncbi.nlm.nih.gov/pubmed/25706642
http://dx.doi.org/10.1371/journal.pone.0117122
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