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Trametinib with or without Vemurafenib in BRAF Mutated Non-Small Cell Lung Cancer

V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) mutated lung cancer is relatively aggressive and is resistant to currently available therapies. In a recent phase II study for patients with BRAF-V600E non-small cell lung cancer (NSCLC), BRAF V600E inhibitor demonstrated evidence of activity, but...

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Detalles Bibliográficos
Autores principales:	Joshi, Monika, Rice, Shawn J., Liu, Xin, Miller, Bruce, Belani, Chandra P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338247/ https://www.ncbi.nlm.nih.gov/pubmed/25706985 http://dx.doi.org/10.1371/journal.pone.0118210

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