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Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies

Ginger is one of the most commonly used herbal medicines for the treatment of numerous ailments and improvement of body functions. It may be used in combination with prescribed drugs. The coadministration of ginger with therapeutic drugs raises a concern of potential deleterious drug interactions vi...

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Detalles Bibliográficos
Autores principales: Qiu, Jia-Xuan, Zhou, Zhi-Wei, He, Zhi-Xu, Zhang, Xueji, Zhou, Shu-Feng, Zhu, Shengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338259/
https://www.ncbi.nlm.nih.gov/pubmed/25733806
http://dx.doi.org/10.2147/DDDT.S74669