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MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E(2)-Mediated M2 Generation

Macrophages dictate both initiation and resolution of inflammation. During acute inflammation classically activated macrophages (M1) predominate, and during the resolution phase alternative macrophages (M2) are dominant. The molecular mechanisms involved in macrophage polarization are understudied....

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Detalles Bibliográficos
Autores principales: Wang, Zhuo, Brandt, Stephanie, Medeiros, Alexandra, Wang, Soujuan, Wu, Hao, Dent, Alexander, Serezani, C. Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338261/
https://www.ncbi.nlm.nih.gov/pubmed/25706647
http://dx.doi.org/10.1371/journal.pone.0115855