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Pluripotency Gene Expression and Growth Control in Cultures of Peripheral Blood Monocytes during Their Conversion into Programmable Cells of Monocytic Origin (PCMO): Evidence for a Regulatory Role of Autocrine Activin and TGF-β

Previous studies have shown that peripheral blood monocytes can be converted in vitro to a stem cell-like cell termed PCMO as evidenced by the re-expression of pluripotency-associated genes, transient proliferation, and the ability to adopt the phenotype of hepatocytes and insulin-producing cells up...

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Detalles Bibliográficos
Autores principales: Ungefroren, Hendrik, Hyder, Ayman, Hinz, Hebke, Groth, Stephanie, Lange, Hans, El-Sayed, Karim M. Fawzy, Ehnert, Sabrina, Nüssler, Andreas K., Fändrich, Fred, Gieseler, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338298/
https://www.ncbi.nlm.nih.gov/pubmed/25707005
http://dx.doi.org/10.1371/journal.pone.0118097