Cargando…

High-calorie diet exacerbates prostate neoplasia in mice with haploinsufficiency of Pten tumor suppressor gene

OBJECTIVE: Association between prostate cancer and obesity remains controversial. Allelic deletions of PTEN, a tumor suppressor gene, are common in prostate cancer in men. Monoallelic Pten deletion in mice causes low prostatic intraepithelial neoplasia (mPIN). This study tested the effect of a hyper...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jehnan, Ramakrishnan, Sadeesh K., Khuder, Saja S., Kaw, Meenakshi K., Muturi, Harrison T., Lester, Sumona Ghosh, Lee, Sang Jun, Fedorova, Larisa V., Kim, Andrea J., Mohamed, Iman E., Gatto-Weis, Cara, Eisenmann, Kathryn M., Conran, Philip B., Najjar, Sonia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338312/ https://www.ncbi.nlm.nih.gov/pubmed/25737954 http://dx.doi.org/10.1016/j.molmet.2014.12.011

Ejemplares similares

PTEN haploinsufficiency and hemangiosarcoma
Publicado: (2012)

SAT-174 Loss of CEACAM1 in Endothelial Cells Causes Hepatic Fibrogenesis
por: Muturi, Harrison, et al.
Publicado: (2019)

Exenatide induces carcinoembryonic antigen‐related cell adhesion molecule 1 expression to prevent hepatic steatosis
por: Ghadieh, Hilda E., et al.
Publicado: (2017)

A new human adipocyte model with PTEN haploinsufficiency
por: Kässner, Franziska, et al.
Publicado: (2020)

Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity
por: Wong, J. T., et al.
Publicado: (2006)

Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma
por: Choorapoikayil, Suma, et al.
Publicado: (2012)

MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia
por: Clarke, M, et al.
Publicado: (2013)

Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice
por: Cabral-Costa, J. V., et al.
Publicado: (2018)

Pten haploinsufficiency disrupts scaling across brain areas during development in mice
por: Clipperton-Allen, Amy E., et al.
Publicado: (2019)

Pten haploinsufficiency causes desynchronized growth of brain areas involved in sensory processing
por: Clipperton-Allen, Amy E., et al.
Publicado: (2022)

Environmental Enrichment Rescues Social Behavioral Deficits and Synaptic Abnormalities in Pten Haploinsufficient Mice
por: Clipperton-Allen, Amy E., et al.
Publicado: (2021)

Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1
por: Muturi, Harrison T., et al.
Publicado: (2021)

Effect of calories-only vs physical activity calorie expenditure labeling on lunch calories purchased in worksite cafeterias
por: Viera, Anthony J., et al.
Publicado: (2019)

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance
por: Al-Share, Qusai Y., et al.
Publicado: (2015)

Mice with null mutation of Ceacam1 develop nonalcoholic steatohepatitis
por: Ghosh, Sumona, et al.
Publicado: (2010)

Mild Obesity, Physical Activity, Calorie Intake, and the Risks of Cervical Intraepithelial Neoplasia and Cervical Cancer
por: Lee, Jae Kwan, et al.
Publicado: (2013)

Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia
por: Fedorova, Larisa, et al.
Publicado: (2012)

Cigarette Smoking among Adolescents in Northwest Ohio: Correlates of Prevalence and Age at Onset
por: Khuder, Sadik A., et al.
Publicado: (2008)

Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue
por: Lester, Sumona G., et al.
Publicado: (2015)

Peroxisome Proliferator-Activated Receptor δ Agonist, HPP593, Prevents Renal Necrosis under Chronic Ischemia
por: Fedorova, Larisa V., et al.
Publicado: (2013)

SAT-151 Hyperinsulinemia-Driven Progressive Metabolic Dysfunction in Male Mice with Liver-Specific CEACAM1 Deletion
por: Ghadieh, Hilda, et al.
Publicado: (2019)

Superimposing Status Epilepticus on Neuron Subset-Specific PTEN Haploinsufficient and Wild Type Mice Results in Long-term Changes in Behavior
por: Smith, Gregory D., et al.
Publicado: (2016)

RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis
por: Bai, Yang, et al.
Publicado: (2019)

The Novel Phosphatidylinositol-3-Kinase (PI3K) Inhibitor Alpelisib Effectively Inhibits Growth of PTEN-Haploinsufficient Lipoma Cells
por: Kirstein, Anna S., et al.
Publicado: (2019)

The Role of PTEN in Epithelial–Mesenchymal Transition
por: Fedorova, Olga, et al.
Publicado: (2022)

Current treatment options for management of anal intraepithelial neoplasia
por: Weis, Stephen E
Publicado: (2013)

Calorie labeling and consumer estimation of calories purchased
por: Taksler, Glen B, et al.
Publicado: (2014)

The Pace of Prostatic Intraepithelial Neoplasia Development Is Determined by the Timing of Pten Tumor Suppressor Gene Excision
por: Luchman, H. Artee, et al.
Publicado: (2008)

Loss of PTEN Signaling in Foxl1(+) Mesenchymal Telocytes Initiates Spontaneous Colonic Neoplasia in Mice
por: Langlois, Marie-Josée, et al.
Publicado: (2019)

A Transition Zone Showing Highly Discontinuous or Alternating Levels of Stem Cell and Proliferation Markers Characterizes the Development of PTEN-Haploinsufficient Colorectal Cancer
por: Arvai, Kevin J., et al.
Publicado: (2015)

A central role for hypoxia-inducible factor (HIF)-2α in hepatic glucose homeostasis
por: Ramakrishnan, Sadeesh K., et al.
Publicado: (2017)

Calorie Restriction Extends Life Span— But Which Calories?
por: Heilbronn, Leonie K, et al.
Publicado: (2005)

The effect of ingredient-specific calorie information on calories ordered
por: Gustafson, Christopher R., et al.
Publicado: (2018)

Intricacies in arrangement of SNP haplotypes suggest “Great Admixture” that created modern humans
por: Dutta, Rajib, et al.
Publicado: (2017)

An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
por: Mirantes, Cristina, et al.
Publicado: (2013)

Calories and carbohydrates /
por: Kraus, Barbara
Publicado: (1983)

Calories and carbohydrates /
por: Kraus, Barbara
Publicado: (1979)

Thinking in Calories
Publicado: (1917)

Calories and Fires
Publicado: (1912)

Mouse models of sporadic thyroid cancer derived from BRAF(V600E) alone or in combination with PTEN haploinsufficiency under physiologic TSH levels
por: Shimamura, Mika, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ife3gg1sipibcpmtmb2849pef9