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Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

OBJECTIVE: Disruption of the genes encoding either seipin or 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2) causes severe congenital generalized lipodystrophy (CGL) in humans. However, the function of seipin in adipogenesis remains poorly defined. We demonstrated recently that seipin can bi...

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Detalles Bibliográficos
Autores principales:	Talukder, Md. Mesbah Uddin, Sim, M.F. Michelle, O'Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338318/ https://www.ncbi.nlm.nih.gov/pubmed/25737955 http://dx.doi.org/10.1016/j.molmet.2014.12.013

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