Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions

In vitro evolution methodologies are powerful approaches to identify RNA with new functionalities. While Systematic Evolution of Ligands by Exponential enrichment (SELEX) is an efficient approach to generate new RNA aptamers, it is less suited for the isolation of efficient ribozymes as it does not...

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Detalles Bibliográficos
Autores principales: Ryckelynck, Michael, Baudrey, Stéphanie, Rick, Christian, Marin, Annick, Coldren, Faith, Westhof, Eric, Griffiths, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338340/
https://www.ncbi.nlm.nih.gov/pubmed/25605963
http://dx.doi.org/10.1261/rna.048033.114

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