Intravenously Injected Human Apolipoprotein A‐I Rapidly Enters the Central Nervous System via the Choroid Plexus

BACKGROUND: Brain lipoprotein metabolism is dependent on lipoprotein particles that resemble plasma high‐density lipoproteins but that contain apolipoprotein (apo) E rather than apoA‐I as their primary protein component. Astrocytes and microglia secrete apoE but not apoA‐I; however, apoA‐I is detect...

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Detalles Bibliográficos
Autores principales: Stukas, Sophie, Robert, Jerome, Lee, Michael, Kulic, Iva, Carr, Michael, Tourigny, Katherine, Fan, Jianjia, Namjoshi, Dhananjay, Lemke, Kalistyne, DeValle, Nicole, Chan, Jeniffer, Wilson, Tammy, Wilkinson, Anna, Chapanian, Rafi, Kizhakkedathu, Jayachandran N., Cirrito, John R., Oda, Michael N., Wellington, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338702/
https://www.ncbi.nlm.nih.gov/pubmed/25392541
http://dx.doi.org/10.1161/JAHA.114.001156

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