Hypertension Is Associated With Preamyloid Oligomers in Human Atrium: A Missing Link in Atrial Pathophysiology?

BACKGROUND: Increasing evidence indicates that proteotoxicity plays a pathophysiologic role in experimental and human cardiomyopathy. In organ‐specific amyloidoses, soluble protein oligomers are the primary cytotoxic species in the process of protein aggregation. While isolated atrial amyloidosis ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Sidorova, Tatiana N., Mace, Lisa C., Wells, K. Sam, Yermalitskaya, Liudmila V., Su, Pei‐Fang, Shyr, Yu, Atkinson, James B., Fogo, Agnes B., Prinsen, Joseph K., Byrne, John G., Petracek, Michael R., Greelish, James P., Hoff, Steven J., Ball, Stephen K., Glabe, Charles G., Brown, Nancy J., Barnett, Joey V., Murray, Katherine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338732/
https://www.ncbi.nlm.nih.gov/pubmed/25468655
http://dx.doi.org/10.1161/JAHA.114.001384

Ejemplares similares

Ejemplares similares