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Traumatic Brain Injury Disrupts Cerebrovascular Tone Through Endothelial Inducible Nitric Oxide Synthase Expression and Nitric Oxide Gain of Function
BACKGROUND: Traumatic brain injury (TBI) has been reported to increase the concentration of nitric oxide (NO) in the brain and can lead to loss of cerebrovascular tone; however, the sources, amounts, and consequences of excess NO on the cerebral vasculature are unknown. Our objective was to elucidat...
Autores principales: | Villalba, Nuria, Sonkusare, Swapnil K., Longden, Thomas A., Tran, Tram L., Sackheim, Adrian M., Nelson, Mark T., Wellman, George C., Freeman, Kalev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338739/ https://www.ncbi.nlm.nih.gov/pubmed/25527626 http://dx.doi.org/10.1161/JAHA.114.001474 |
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