Cargando…

Intraosseous and intravenous administration of antibiotics yields comparable plasma concentrations during experimental septic shock

BACKGROUND: We aimed to investigate whether comparable antibiotic concentrations could be reached with intraosseous and intravenous administration during septic shock. METHODS: In this randomized, prospective experimental study conducted at an animal research laboratory at the University Hospital of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strandberg, G, Larsson, A, Lipcsey, M, Michalek, J, Eriksson, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Intensive Care and Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338763/ https://www.ncbi.nlm.nih.gov/pubmed/25557933 http://dx.doi.org/10.1111/aas.12454

Ejemplares similares

Protocol for a systematic review and meta-analysis assessing conservative versus liberal intravenous fluid administration in patients with sepsis or septic shock at risk of fluid overload
por: Bharwani, Aadil, et al.
Publicado: (2023)

The swedish covid‐19 intensive care cohort: Risk factors of ICU admission and ICU mortality
por: Ahlström, Björn, et al.
Publicado: (2021)

Estimated glomerular filtration rates are higher when creatinine‐based equations are compared with a cystatin C‐based equation in coronavirus disease 2019
por: Larsson, Anders O., et al.
Publicado: (2022)

The premature closure of ROMPA clinical trial: mortality reduction in septic shock by plasma adsorption
por: Giménez-Esparza, Carola, et al.
Publicado: (2019)

Protocolised reduction of non-resuscitation fluids versus usual care in patients with septic shock (REDUSE): a protocol for a multicentre feasibility trial
por: Lindén, Anja, et al.
Publicado: (2023)

Mortality Reduction in Septic Shock by Plasma Adsorption (ROMPA): a protocol for a randomised clinical trial
por: Colomina-Climent, Francisco, et al.
Publicado: (2016)

Efficacy of coupled plasma filtration adsorption (CPFA) in patients with septic shock: A multicenter randomised controlled clinical trial
por: Livigni, Sergio, et al.
Publicado: (2014)

Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial
por: Rochwerg, Bram, et al.
Publicado: (2017)

Intensive care‐treated COVID‐19 patients’ perception of their illness and remaining symptoms
por: Wallin, Ewa, et al.
Publicado: (2021)

Effect of levosimendan on mortality in severe sepsis and septic shock: a meta-analysis of randomised trials
por: Chang, Wei, et al.
Publicado: (2018)

COVID‐19 patients in intensive care develop predominantly oliguric acute kidney injury
por: Luther, Tomas, et al.
Publicado: (2020)

Protocol for a randomised controlled trial of VAsopressin versus Noradrenaline as Initial therapy in Septic sHock (VANISH)
por: Gordon, Anthony C, et al.
Publicado: (2014)

Study into the reversal of septic shock with landiolol (beta blockade): STRESS-L Study protocol for a randomised trial
por: Lall, Ranjit, et al.
Publicado: (2021)

Multicountry survey of emergency and critical care medicine physicians’ fluid resuscitation practices for adult patients with early septic shock
por: McIntyre, Lauralyn, et al.
Publicado: (2016)

Dosing of Extracorporeal Cytokine Removal In Septic Shock (DECRISS): protocol of a prospective, randomised, adaptive, multicentre clinical trial
por: Kanjo, Anna, et al.
Publicado: (2021)

Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial
por: Francois, Bruno, et al.
Publicado: (2021)

Doppler identified venous congestion in septic shock: protocol for an international, multi-centre prospective cohort study (Andromeda-VEXUS)
por: Prager, Ross, et al.
Publicado: (2023)

Are large randomised controlled trials in severe sepsis and septic shock statistically disadvantaged by repeated inadvertent underestimates of required sample size?
por: Wong, Joshua L C, et al.
Publicado: (2018)

Vitamin C therapy for patients with sepsis or septic shock: a protocol for a systematic review and a network meta-analysis
por: Fujii, Tomoko, et al.
Publicado: (2019)

Vascular Reactivity Index and PELOD-2 as a mortality predictor in paediatric septic shock: a single-centre retrospective study
por: Yuniar, Irene, et al.
Publicado: (2022)

A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2)
por: Geven, Christopher, et al.
Publicado: (2019)

Effect of early goal-directed therapy on mortality in patients with severe sepsis or septic shock: a meta-analysis of randomised controlled trials
por: Yu, Hong, et al.
Publicado: (2016)

Polymyxin B-immobilised haemoperfusion and mortality in critically ill patients with sepsis/septic shock: a protocol for a systematic review and meta-analysis
por: Fujii, Tomoko, et al.
Publicado: (2016)

Prospective longitudinal observational study of the macro and micro haemodynamic responses to septic shock in the renal and systemic circulations: a protocol for the MICROSHOCK – RENAL study
por: Watchorn, Jim, et al.
Publicado: (2019)

Recombinant human activated protein C for the treatment of severe sepsis and septic shock: a study protocol for incorporating observational evidence using a Bayesian approach
por: Zhang, Zhongheng
Publicado: (2014)

Targeting skeletal muscle tissue oxygenation (StO(2)) in adults with severe sepsis and septic shock: a randomised controlled trial (OTO-StS Study)
por: Nardi, Olivier, et al.
Publicado: (2018)

Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data
por: Annane, Djillali, et al.
Publicado: (2020)

Zero expiratory pressure and low oxygen concentration promote heterogeneity of regional ventilation and lung densities
por: Borges, J. B., et al.
Publicado: (2016)

Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study
por: Balik, Martin, et al.
Publicado: (2019)

Effects of evidence-based ICU care on long-term outcomes of patients with sepsis or septic shock (ILOSS): protocol for a multicentre prospective observational cohort study in Japan
por: Liu, Keibun, et al.
Publicado: (2022)

LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock
por: Guirgis, Faheem W, et al.
Publicado: (2019)

The effect of hemorrhagic shock and intraosseous adrenaline injection on the delivery of a subsequently administered drug - an experimental study
por: Eriksson, Mats, et al.
Publicado: (2019)

Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
por: Biagioni, Emanuela, et al.
Publicado: (2021)

Markers of tissue hypoperfusion in pediatric septic shock
por: Dugas, M. -A., et al.
Publicado: (2000)

Characteristics and outcomes of patients with COVID‐19 admitted to ICU in a tertiary hospital in Stockholm, Sweden
por: Larsson, Emma, et al.
Publicado: (2020)

Association between minimal decrease in platelet counts and outcomes in septic patients: a retrospective observational study
por: Liu, Xing, et al.
Publicado: (2023)

Hypotonic and isotonic intravenous maintenance fluids in hospitalised paediatric patients: a randomised controlled trial
por: Torres, Silvio Fabio, et al.
Publicado: (2019)

Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis)
por: Scott, Jonathan, et al.
Publicado: (2022)

Haemodynamic response to crystalloids or colloids in shock: an exploratory subgroup analysis of a randomised controlled trial
por: Heming, Nicholas, et al.
Publicado: (2017)

Paediatric dengue shock syndrome and acute respiratory failure: a single-centre retrospective study
por: Preeprem, Nutnicha, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vqu8qvf8lmglohhvj3isfk38ml