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Cuprizone does not induce CNS demyelination in nonhuman primates
Cognitive decline is a common symptom in multiple sclerosis patients, with profound effects on the quality of life. A nonhuman primate model of multiple sclerosis would be best suited to test the effects of demyelination on complex cognitive functions such as learning and reasoning. Cuprizone has be...
Autores principales: | Chen, Zhihong, Chen, Jacqueline T, Johnson, Matthew, Gossman, Zachary C, Hendrickson, Megan, Sakaie, Ken, Martinez-Rubio, Clarissa, Gale, John T, Trapp, Bruce D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338961/ https://www.ncbi.nlm.nih.gov/pubmed/25750925 http://dx.doi.org/10.1002/acn3.159 |
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