Cargando…

The Alarmin IL-33 Promotes Regulatory T Cell Function in the Intestine

Foxp3(+) regulatory T cells are abundant in the intestine where they prevent dysregulated inflammatory responses to self and environmental stimuli. It is now appreciated that T(reg) cells acquire tissue-specific adaptations that facilitate their survival and function(1); however, key host factors co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schiering, Chris, Krausgruber, Thomas, Chomka, Agnieszka, Fröhlich, Anja, Adelmann, Krista, Wohlfert, Elizabeth A., Pott, Johanna, Griseri, Thibault, Bollrath, Julia, Hegazy, Ahmed N., Harrison, Oliver J., Owens, Benjamin M.J., Löhning, Max, Belkaid, Yasmine, Fallon, Padraic G., Powrie, Fiona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339042/ https://www.ncbi.nlm.nih.gov/pubmed/25043027 http://dx.doi.org/10.1038/nature13577

Ejemplares similares

Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling
por: Ilott, Nicholas Edward, et al.
Publicado: (2016)

Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling
por: Ilott, Nicholas Edward, et al.
Publicado: (2019)

T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine
por: Krausgruber, Thomas, et al.
Publicado: (2016)

Memory CD8(+) T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals
por: Baumann, Claudia, et al.
Publicado: (2019)

Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation
por: Griseri, Thibault, et al.
Publicado: (2012)

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis
por: Griseri, Thibault, et al.
Publicado: (2015)

IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors
por: Swann, James W., et al.
Publicado: (2020)

Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3(+) Treg cell function in the intestine
por: Harrison, OJ, et al.
Publicado: (2015)

Sound the Alarmin: Interleukin-33 Commandeers the Gastric Immune Response
por: Noto, Jennifer M., et al.
Publicado: (2015)

OX40 is required for regulatory T cell–mediated control of colitis
por: Griseri, Thibault, et al.
Publicado: (2010)

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
por: Cohen, E. Suzanne, et al.
Publicado: (2015)

Sounding the alarmins—The role of alarmin cytokines in asthma
por: Gauvreau, Gail M., et al.
Publicado: (2022)

The Role of Alarmins in Osteoarthritis Pathogenesis: HMGB1, S100B and IL-33
por: Palumbo, Antonino, et al.
Publicado: (2023)

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release
por: Siede, Julia, et al.
Publicado: (2016)

Schizophrenia and Alarmins
por: Ma, Huan, et al.
Publicado: (2022)

Alarmin’ Immunologists: IL-33 as a Putative Target for Modulating T Cell-Dependent Responses
por: Gajardo Carrasco, Tania, et al.
Publicado: (2015)

Alarmins in Osteoporosis, RAGE, IL-1, and IL-33 Pathways: A Literature Review
por: De Martinis, Massimo, et al.
Publicado: (2020)

The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration
por: Cosway, Emilie J., et al.
Publicado: (2023)

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins
por: Bertheloot, Damien, et al.
Publicado: (2017)

The Impact of Invariant NKT Cells in Sterile Inflammation: The Possible Contribution of the Alarmin/Cytokine IL-33
por: Ferhat, Maroua Haroun, et al.
Publicado: (2018)

IL-33 and its increased serum levels as an alarmin for imminent pulmonary complications in polytraumatized patients
por: Halát, Gabriel, et al.
Publicado: (2019)

IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease
por: Perez, Federico, et al.
Publicado: (2020)

Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
por: Gundersen, Mona Dixon, et al.
Publicado: (2022)

CD4(+) T-cell subsets in intestinal inflammation
por: Shale, Matthew, et al.
Publicado: (2013)

When Alarmins Are “Therapeutic”
por: Vinchi, Francesca
Publicado: (2020)

Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
por: Miragaia, Ricardo J., et al.
Publicado: (2019)

IL33 Is a Stomach Alarmin That Initiates a Skewed Th2 Response to Injury and Infection
por: Buzzelli, Jon N., et al.
Publicado: (2015)

Alarmins HMGB1, IL-33, S100A7, and S100A12 in Psoriasis Vulgaris
por: Borsky, Pavel, et al.
Publicado: (2020)

Alarmin IL-33 orchestrates antitumoral T cell responses to enhance sensitivity to 5-fluorouracil in colorectal cancer
por: Song, Mengjia, et al.
Publicado: (2023)

Nuclear Alarmin Cytokines in Inflammation
por: Jiang, Lili, et al.
Publicado: (2020)

Alarmins, COVID-19 and comorbidities
por: Di Salvo, Eleonora, et al.
Publicado: (2021)

The Alarmin Concept Applied to Human Renal Transplantation: Evidence for a Differential Implication of HMGB1 and IL-33
por: Thierry, Antoine, et al.
Publicado: (2014)

Endogenous Interleukin-33 Acts as an Alarmin in Liver Ischemia-Reperfusion and Is Associated With Injury After Human Liver Transplantation
por: Barbier, Louise, et al.
Publicado: (2021)

Activation of Eosinophils Interacting with Dermal Fibroblasts by Pruritogenic Cytokine IL-31 and Alarmin IL-33: Implications in Atopic Dermatitis
por: Wong, Chun-Kwok, et al.
Publicado: (2012)

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage
por: Scott, Ian C., et al.
Publicado: (2018)

The Multitasking Potential of Alarmins and Atypical Chemokines
por: Kapurniotu, Aphrodite, et al.
Publicado: (2019)

Role of Alarmins in the Pathogenesis of Systemic Sclerosis
por: Giovannetti, Antonello, et al.
Publicado: (2020)

The Involvement of Alarmins in the Pathogenesis of Sjögren’s Syndrome
por: Sarrand, Julie, et al.
Publicado: (2022)

Replicating viral vector platform exploits alarmin signals for potent CD8(+) T cell-mediated tumour immunotherapy
por: Kallert, Sandra M., et al.
Publicado: (2017)

IL-33, an Alarmin of the IL-1 Family Involved in Allergic and Non Allergic Inflammation: Focus on the Mechanisms of Regulation of Its Activity
por: Cayrol, Corinne
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ask48p1avvrt859108o5mug9b9