It's cold, mom! It's cyclic GMP

Cyclic GMP is the signal transducer of a family of transmembrane, particulate guanylyl cyclase (GC) receptors with key roles in physiology and disease. GC-G, the last member of the membrane GCs identified in mammals, is an orphan receptor and its regulation and function have remained largely unknown...

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Detalles Bibliográficos
Autor principal: Kuhn, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Have You Seen?
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339115/
https://www.ncbi.nlm.nih.gov/pubmed/25555793
http://dx.doi.org/10.15252/embj.201490639
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author Kuhn, Michaela
author_facet Kuhn, Michaela
author_sort Kuhn, Michaela
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description Cyclic GMP is the signal transducer of a family of transmembrane, particulate guanylyl cyclase (GC) receptors with key roles in physiology and disease. GC-G, the last member of the membrane GCs identified in mammals, is an orphan receptor and its regulation and function have remained largely unknown. In this issue of The EMBO Journal, Chao et al (2015) show that the GC-G/cGMP pathway, which is expressed in a specific cluster of olfactory neurons of neonatal mice, functions as a cold-induced thermosensor, which triggers protective maternal care.
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spelling pubmed-43391152015-11-27 It's cold, mom! It's cyclic GMP Kuhn, Michaela EMBO J Have You Seen? Cyclic GMP is the signal transducer of a family of transmembrane, particulate guanylyl cyclase (GC) receptors with key roles in physiology and disease. GC-G, the last member of the membrane GCs identified in mammals, is an orphan receptor and its regulation and function have remained largely unknown. In this issue of The EMBO Journal, Chao et al (2015) show that the GC-G/cGMP pathway, which is expressed in a specific cluster of olfactory neurons of neonatal mice, functions as a cold-induced thermosensor, which triggers protective maternal care. BlackWell Publishing Ltd 2015-02-03 2015-01-02 /pmc/articles/PMC4339115/ /pubmed/25555793 http://dx.doi.org/10.15252/embj.201490639 Text en © 2015 The Author. Published under the terms of the CC BY NC ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Have You Seen?
Kuhn, Michaela
It's cold, mom! It's cyclic GMP
title It's cold, mom! It's cyclic GMP
title_full It's cold, mom! It's cyclic GMP
title_fullStr It's cold, mom! It's cyclic GMP
title_full_unstemmed It's cold, mom! It's cyclic GMP
title_short It's cold, mom! It's cyclic GMP
title_sort it's cold, mom! it's cyclic gmp
topic Have You Seen?
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339115/
https://www.ncbi.nlm.nih.gov/pubmed/25555793
http://dx.doi.org/10.15252/embj.201490639
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