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Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK
Numerous extrinsic and intrinsic insults trigger the HSF1-mediated proteotoxic stress response (PSR), an ancient transcriptional program that is essential to proteostasis and survival under such conditions. In contrast to its well-recognized mobilization by proteotoxic stress, little is known about...
Autores principales: | Dai, Siyuan, Tang, Zijian, Cao, Junyue, Zhou, Wei, Li, Huawen, Sampson, Stephen, Dai, Chengkai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339117/ https://www.ncbi.nlm.nih.gov/pubmed/25425574 http://dx.doi.org/10.15252/embj.201489062 |
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