Per-Oral Immunization with Antigen-Conjugated Nanoparticles followed by Sub-Cutaneous Boosting Immunization Induces Long-Lasting Mucosal and Systemic Antibody Responses in Mice

Food or water-borne enteric pathogens invade their hosts via intestinal mucosal surfaces, thus developing effective oral vaccines would greatly reduce the burden of infectious diseases. The nature of the antigen, as well as the mode of its internalization in the intestinal mucosa affects the ensuing...

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Detalles Bibliográficos
Autores principales: Howe, Savannah E., Konjufca, Vjollca H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339372/
https://www.ncbi.nlm.nih.gov/pubmed/25710518
http://dx.doi.org/10.1371/journal.pone.0118067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339372/
https://www.ncbi.nlm.nih.gov/pubmed/25710518
http://dx.doi.org/10.1371/journal.pone.0118067

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