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Hyperglycemia diverts dividing stem cells to pathological adipogenesis

This commentary proposes a mechanism for why murine diabetic adipose tissue contains very few remaining stem cells compared with normal adipose tissue. The mechanism involves the diversion of stem cells to pathological adipocytes when they divide in hyperglycemia.

Detalles Bibliográficos
Autores principales: Hascall, Vincent, Wang, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339424/
https://www.ncbi.nlm.nih.gov/pubmed/25689074
http://dx.doi.org/10.1186/scrt518