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Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs
The human artificial chromosome (HAC) vector is a promising tool to improve the problematic suppression and position effects of transgene expression frequently seen in transgenic cells and animals produced by conventional plasmid or viral vectors. We generated transgenic mice maintaining a single HA...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339693/ https://www.ncbi.nlm.nih.gov/pubmed/25308419 http://dx.doi.org/10.1007/s00412-014-0488-3 |