Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs

The human artificial chromosome (HAC) vector is a promising tool to improve the problematic suppression and position effects of transgene expression frequently seen in transgenic cells and animals produced by conventional plasmid or viral vectors. We generated transgenic mice maintaining a single HA...

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Detalles Bibliográficos
Autores principales: Hasegawa, Yoshinori, Ishikura, Tomoyuki, Hasegawa, Takanori, Watanabe, Takashi, Suzuki, Junpei, Nakayama, Manabu, Okamura, Yoshiaki, Okazaki, Tuneko, Koseki, Haruhiko, Ohara, Osamu, Ikeno, Masashi, Masumoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339693/
https://www.ncbi.nlm.nih.gov/pubmed/25308419
http://dx.doi.org/10.1007/s00412-014-0488-3

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