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DNaseI Protects against Paraquat-Induced Acute Lung Injury and Pulmonary Fibrosis Mediated by Mitochondrial DNA

Background. Paraquat (PQ) poisoning is a lethal toxicological challenge that served as a disease model of acute lung injury and pulmonary fibrosis, but the mechanism is undetermined and no effective treatment has been discovered. Methods and Findings. We demonstrated that PQ injures mitochondria and...

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Detalles Bibliográficos
Autores principales:	Li, Guo, Yuzhen, Li, Yi, Chen, Xiaoxiang, Chen, Wei, Zhou, Changqing, Zhu, Shuang, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339792/ https://www.ncbi.nlm.nih.gov/pubmed/25759818 http://dx.doi.org/10.1155/2015/386952

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