Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases

Most anti-N antibodies are naturally occurring, IgM antibodies, and not active above 25°C and are not clinically significant but IgG anti- N has also been described. Immune anti-N resulting from multiple transfusions does occur & has been implicated as the cause of hemolytic transfusion reaction...

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Autores principales: Kumawat, Vijay, Jain, Ashish, Marwaha, Neelam, Sharma, Ratti Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339945/
https://www.ncbi.nlm.nih.gov/pubmed/25722584
http://dx.doi.org/10.4103/0973-6247.150964
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author Kumawat, Vijay
Jain, Ashish
Marwaha, Neelam
Sharma, Ratti Ram
author_facet Kumawat, Vijay
Jain, Ashish
Marwaha, Neelam
Sharma, Ratti Ram
author_sort Kumawat, Vijay
collection PubMed
description Most anti-N antibodies are naturally occurring, IgM antibodies, and not active above 25°C and are not clinically significant but IgG anti- N has also been described. Immune anti-N resulting from multiple transfusions does occur & has been implicated as the cause of hemolytic transfusion reactions and mild hemolytic disease of fetus and newborn. Anti- N reacting at room temperature can be a cause for ABO blood group discrepancy
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spelling pubmed-43399452015-02-26 Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases Kumawat, Vijay Jain, Ashish Marwaha, Neelam Sharma, Ratti Ram Asian J Transfus Sci Case Report Most anti-N antibodies are naturally occurring, IgM antibodies, and not active above 25°C and are not clinically significant but IgG anti- N has also been described. Immune anti-N resulting from multiple transfusions does occur & has been implicated as the cause of hemolytic transfusion reactions and mild hemolytic disease of fetus and newborn. Anti- N reacting at room temperature can be a cause for ABO blood group discrepancy Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4339945/ /pubmed/25722584 http://dx.doi.org/10.4103/0973-6247.150964 Text en Copyright: © Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kumawat, Vijay
Jain, Ashish
Marwaha, Neelam
Sharma, Ratti Ram
Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
title Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
title_full Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
title_fullStr Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
title_full_unstemmed Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
title_short Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
title_sort anti-n antibody reacting at 37°c: an unusual occurrence interfering with routine testing: two interesting cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339945/
https://www.ncbi.nlm.nih.gov/pubmed/25722584
http://dx.doi.org/10.4103/0973-6247.150964
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AT marwahaneelam antinantibodyreactingat37canunusualoccurrenceinterferingwithroutinetestingtwointerestingcases
AT sharmarattiram antinantibodyreactingat37canunusualoccurrenceinterferingwithroutinetestingtwointerestingcases

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