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High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice(1)(2)(3)(4)(5)

Background: Increased consumption of folic acid is prevalent, leading to concerns about negative consequences. The effects of folic acid on the liver, the primary organ for folate metabolism, are largely unknown. Methylenetetrahydrofolate reductase (MTHFR) provides methyl donors for S-adenosylmethio...

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Detalles Bibliográficos
Autores principales:	Christensen, Karen E, Mikael, Leonie G, Leung, Kit-Yi, Lévesque, Nancy, Deng, Liyuan, Wu, Qing, Malysheva, Olga V, Best, Ana, Caudill, Marie A, Greene, Nicholas DE, Rozen, Rima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Nutrition 2015
Materias:	Gene-Nutrient Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340065/ https://www.ncbi.nlm.nih.gov/pubmed/25733650 http://dx.doi.org/10.3945/ajcn.114.086603

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