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Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survival

Re-expression of E2 in human papillomavirus (HPV) transformed tumour cells can induce apoptosis; however, some evidences also attribute an important role to E2 in sustaining tumorigenesis. In the present paper, we studied the effects of tumour necrosis factor (TNF)-α-mediated NF-κB (nuclear factor k...

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Detalles Bibliográficos
Autores principales: Prabhavathy, Devan, Subramanian, Chandrasekaran Karthik, Karunagaran, Devarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340273/
https://www.ncbi.nlm.nih.gov/pubmed/25572145
http://dx.doi.org/10.1042/BSR20140160