Cargando…
The glutaredoxin mono- and di-thiol mechanisms for deglutathionylation are functionally equivalent: implications for redox systems biology
Glutathionylation plays a central role in cellular redox regulation and anti-oxidative defence. Grx (Glutaredoxins) are primarily responsible for reversing glutathionylation and their activity therefore affects a range of cellular processes, making them prime candidates for computational systems bio...
Autores principales: | Mashamaite, Lefentse N., Rohwer, Johann M., Pillay, Ché S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340274/ https://www.ncbi.nlm.nih.gov/pubmed/25514238 http://dx.doi.org/10.1042/BSR20140157 |
Ejemplares similares
-
Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system x(C)(−)
por: Aboushousha, Reem, et al.
Publicado: (2023) -
Can thiol-based redox systems be utilized as parts for synthetic biology applications?
por: Pillay, Ché S., et al.
Publicado: (2021) -
ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation
por: Li, Shuhang, et al.
Publicado: (2021) -
Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches
por: López-Grueso, MJ, et al.
Publicado: (2018) -
Glutaredoxin: Discovery, redox defense and much more
por: Ogata, Fernando T., et al.
Publicado: (2021)