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Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options

Virus-specific CD8(+) T cells play an important role in controlling viral infections including human immunodeficiency virus (HIV) infection. However, during chronic HIV infection, virus-specific CD8(+) T cells undergo functional exhaustion, lose effector functions and fail to control viral infection...

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Detalles Bibliográficos
Autores principales:	Velu, Vijayakumar, Shetty, Ravi Dyavar, Larsson, Marie, Shankar, Esaki M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340294/ https://www.ncbi.nlm.nih.gov/pubmed/25756928 http://dx.doi.org/10.1186/s12977-015-0144-x

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