Cargando…
Fluorogen-Activating Proteins Provide Tunable Labeling Densities for Tracking FcεRI Independent of IgE
[Image: see text] Crosslinking of IgE bound FcεRI on mast cells and basophils by multivalent antigen leads to degranulation and the release of key inflammatory mediators that stimulate the allergic response. Here, we present and characterize the use of fluorogen-activating proteins (FAPs) for single...
Autores principales: | Schwartz, Samantha L., Yan, Qi, Telmer, Cheryl A., Lidke, Keith A., Bruchez, Marcel P., Lidke, Diane S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340345/ https://www.ncbi.nlm.nih.gov/pubmed/25343439 http://dx.doi.org/10.1021/cb5005146 |
Ejemplares similares
-
Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1
por: Kanagy, William K., et al.
Publicado: (2022) -
Differential mast cell outcomes are sensitive to FcεRI-Syk binding kinetics
por: Schwartz, Samantha L., et al.
Publicado: (2017) -
Antigen Geometry Tunes Mast Cell Signaling Through Distinct FcεRI Aggregation and Structural Changes
por: Rinaldi, Derek A., et al.
Publicado: (2023) -
Combinatorial diversity of Syk recruitment driven by its multivalent engagement with FcεRIγ
por: Travers, Timothy, et al.
Publicado: (2019) -
Regulation of Trafficking and Signaling of the High Affinity IgE Receptor by FcεRIβ and the Potential Impact of FcεRIβ Splicing in Allergic Inflammation
por: Arthur, Greer K., et al.
Publicado: (2022)