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Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
Intracranial brain parenchymal tuberculomas may form paradoxically, days to months after starting antituberculous drug therapy. They may develop in and around optic chiasm and optic nerves after antituberculous treatment as a quite rare occurrence in tuberculous meningitis (TBM) this may lead to sev...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medical University Publishing House Craiova
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340446/ https://www.ncbi.nlm.nih.gov/pubmed/25729611 http://dx.doi.org/10.12865/CHSJ.40.03.14 |
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author | AHMETGJEKAJ, ILIR KABASHI-MUÇAJ, SERBEZE LASCU, LUANA CORINA BONDARI, SIMONA BONDARI, A. |
author_facet | AHMETGJEKAJ, ILIR KABASHI-MUÇAJ, SERBEZE LASCU, LUANA CORINA BONDARI, SIMONA BONDARI, A. |
author_sort | AHMETGJEKAJ, ILIR |
collection | PubMed |
description | Intracranial brain parenchymal tuberculomas may form paradoxically, days to months after starting antituberculous drug therapy. They may develop in and around optic chiasm and optic nerves after antituberculous treatment as a quite rare occurrence in tuberculous meningitis (TBM) this may lead to severe visual loss if not treated properly. We describe a 5 year-old child with documented TBM being treated with first line antituberculous drugs which developed visual impairment 3 months after starting the treatment. MRI after gadolinium administration revealed multiple perichiasmatic ring enhancing lesions due to tuberculomas. Visual impairment developing in a patient on treatment with antituberculous drugs should give rise to a suspicion of rare optochiasmatic tuberculomas; this necessitates urgent contrast-enhanced MRI of the brain and prompt treatment with steroids. |
format | Online Article Text |
id | pubmed-4340446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medical University Publishing House Craiova |
record_format | MEDLINE/PubMed |
spelling | pubmed-43404462015-02-27 Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis AHMETGJEKAJ, ILIR KABASHI-MUÇAJ, SERBEZE LASCU, LUANA CORINA BONDARI, SIMONA BONDARI, A. Curr Health Sci J Case Reports Intracranial brain parenchymal tuberculomas may form paradoxically, days to months after starting antituberculous drug therapy. They may develop in and around optic chiasm and optic nerves after antituberculous treatment as a quite rare occurrence in tuberculous meningitis (TBM) this may lead to severe visual loss if not treated properly. We describe a 5 year-old child with documented TBM being treated with first line antituberculous drugs which developed visual impairment 3 months after starting the treatment. MRI after gadolinium administration revealed multiple perichiasmatic ring enhancing lesions due to tuberculomas. Visual impairment developing in a patient on treatment with antituberculous drugs should give rise to a suspicion of rare optochiasmatic tuberculomas; this necessitates urgent contrast-enhanced MRI of the brain and prompt treatment with steroids. Medical University Publishing House Craiova 2014 2014-08-04 /pmc/articles/PMC4340446/ /pubmed/25729611 http://dx.doi.org/10.12865/CHSJ.40.03.14 Text en Copyright © 2014, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited. |
spellingShingle | Case Reports AHMETGJEKAJ, ILIR KABASHI-MUÇAJ, SERBEZE LASCU, LUANA CORINA BONDARI, SIMONA BONDARI, A. Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis |
title | Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis |
title_full | Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis |
title_fullStr | Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis |
title_full_unstemmed | Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis |
title_short | Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis |
title_sort | paradoxical growth of optochiasmatic tuberculoma during the treatment of tuberculous meningitis |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340446/ https://www.ncbi.nlm.nih.gov/pubmed/25729611 http://dx.doi.org/10.12865/CHSJ.40.03.14 |
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