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Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis

Intracranial brain parenchymal tuberculomas may form paradoxically, days to months after starting antituberculous drug therapy. They may develop in and around optic chiasm and optic nerves after antituberculous treatment as a quite rare occurrence in tuberculous meningitis (TBM) this may lead to sev...

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Autores principales: AHMETGJEKAJ, ILIR, KABASHI-MUÇAJ, SERBEZE, LASCU, LUANA CORINA, BONDARI, SIMONA, BONDARI, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340446/
https://www.ncbi.nlm.nih.gov/pubmed/25729611
http://dx.doi.org/10.12865/CHSJ.40.03.14
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author AHMETGJEKAJ, ILIR
KABASHI-MUÇAJ, SERBEZE
LASCU, LUANA CORINA
BONDARI, SIMONA
BONDARI, A.
author_facet AHMETGJEKAJ, ILIR
KABASHI-MUÇAJ, SERBEZE
LASCU, LUANA CORINA
BONDARI, SIMONA
BONDARI, A.
author_sort AHMETGJEKAJ, ILIR
collection PubMed
description Intracranial brain parenchymal tuberculomas may form paradoxically, days to months after starting antituberculous drug therapy. They may develop in and around optic chiasm and optic nerves after antituberculous treatment as a quite rare occurrence in tuberculous meningitis (TBM) this may lead to severe visual loss if not treated properly. We describe a 5 year-old child with documented TBM being treated with first line antituberculous drugs which developed visual impairment 3 months after starting the treatment. MRI after gadolinium administration revealed multiple perichiasmatic ring enhancing lesions due to tuberculomas. Visual impairment developing in a patient on treatment with antituberculous drugs should give rise to a suspicion of rare optochiasmatic tuberculomas; this necessitates urgent contrast-enhanced MRI of the brain and prompt treatment with steroids.
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spelling pubmed-43404462015-02-27 Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis AHMETGJEKAJ, ILIR KABASHI-MUÇAJ, SERBEZE LASCU, LUANA CORINA BONDARI, SIMONA BONDARI, A. Curr Health Sci J Case Reports Intracranial brain parenchymal tuberculomas may form paradoxically, days to months after starting antituberculous drug therapy. They may develop in and around optic chiasm and optic nerves after antituberculous treatment as a quite rare occurrence in tuberculous meningitis (TBM) this may lead to severe visual loss if not treated properly. We describe a 5 year-old child with documented TBM being treated with first line antituberculous drugs which developed visual impairment 3 months after starting the treatment. MRI after gadolinium administration revealed multiple perichiasmatic ring enhancing lesions due to tuberculomas. Visual impairment developing in a patient on treatment with antituberculous drugs should give rise to a suspicion of rare optochiasmatic tuberculomas; this necessitates urgent contrast-enhanced MRI of the brain and prompt treatment with steroids. Medical University Publishing House Craiova 2014 2014-08-04 /pmc/articles/PMC4340446/ /pubmed/25729611 http://dx.doi.org/10.12865/CHSJ.40.03.14 Text en Copyright © 2014, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Case Reports
AHMETGJEKAJ, ILIR
KABASHI-MUÇAJ, SERBEZE
LASCU, LUANA CORINA
BONDARI, SIMONA
BONDARI, A.
Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
title Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
title_full Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
title_fullStr Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
title_full_unstemmed Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
title_short Paradoxical Growth of Optochiasmatic Tuberculoma during the Treatment of Tuberculous Meningitis
title_sort paradoxical growth of optochiasmatic tuberculoma during the treatment of tuberculous meningitis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340446/
https://www.ncbi.nlm.nih.gov/pubmed/25729611
http://dx.doi.org/10.12865/CHSJ.40.03.14
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