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Comparison of a PfHRP2-based rapid diagnostic test and PCR for malaria in a low prevalence setting in rural southern Zambia: implications for elimination

BACKGROUND: Rapid diagnostic tests (RDTs) detecting histidine-rich protein 2 (PfHRP2) antigen are used to identify individuals with Plasmodium falciparum infection even in low transmission settings seeking to achieve elimination. However, these RDTs lack sensitivity to detect low-density infections,...

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Detalles Bibliográficos
Autores principales: Laban, Natasha M, Kobayashi, Tamaki, Hamapumbu, Harry, Sullivan, David, Mharakurwa, Sungano, Thuma, Philip E, Shiff, Clive J, Moss, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340619/
https://www.ncbi.nlm.nih.gov/pubmed/25888818
http://dx.doi.org/10.1186/s12936-015-0544-3