Ca(2+) permeation and/or binding to Ca(V)1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function

BACKGROUND: Ca(2+) influx through Ca(V)1.1 is not required for skeletal muscle excitation-contraction coupling, but whether Ca(2+) permeation through Ca(V)1.1 during sustained muscle activity plays a functional role in mammalian skeletal muscle has not been assessed. METHODS: We generated a mouse wi...

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Detalles Bibliográficos
Autores principales: Lee, Chang Seok, Dagnino-Acosta, Adan, Yarotskyy, Viktor, Hanna, Amy, Lyfenko, Alla, Knoblauch, Mark, Georgiou, Dimitra K, Poché, Ross A, Swank, Michael W, Long, Cheng, Ismailov, Iskander I, Lanner, Johanna, Tran, Ted, Dong, KeKe, Rodney, George G, Dickinson, Mary E, Beeton, Christine, Zhang, Pumin, Dirksen, Robert T, Hamilton, Susan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340672/
https://www.ncbi.nlm.nih.gov/pubmed/25717360
http://dx.doi.org/10.1186/s13395-014-0027-1

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