Cargando…

IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation

BACKGROUND: Interleukin-27 (IL-27) is a multifunctional cytokine with both pro-inflammatory and immunoregulatory functions. At present, the role of IL-27 in pulmonary fibrosis remains unknown. METHODS: In this study, we observed the expression of IL-27/IL-27R in a mouse model of bleomycin (BLM)-indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Zhaoxing, Lu, Xin, Yang, Yanni, Zhang, Tao, Li, Yongxia, Chai, Yanlin, Lei, Wen, Li, Changbo, Ai, Li, Tai, Wenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340860/
https://www.ncbi.nlm.nih.gov/pubmed/25888222
http://dx.doi.org/10.1186/s12890-015-0012-4