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IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation

BACKGROUND: Interleukin-27 (IL-27) is a multifunctional cytokine with both pro-inflammatory and immunoregulatory functions. At present, the role of IL-27 in pulmonary fibrosis remains unknown. METHODS: In this study, we observed the expression of IL-27/IL-27R in a mouse model of bleomycin (BLM)-indu...

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Detalles Bibliográficos
Autores principales:	Dong, Zhaoxing, Lu, Xin, Yang, Yanni, Zhang, Tao, Li, Yongxia, Chai, Yanlin, Lei, Wen, Li, Changbo, Ai, Li, Tai, Wenlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340860/ https://www.ncbi.nlm.nih.gov/pubmed/25888222 http://dx.doi.org/10.1186/s12890-015-0012-4

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