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Increased Risk of Genetic and Epigenetic Instability in Human Embryonic Stem Cells Associated with Specific Culture Conditions
The self-renewal and differentiation capacities of human pluripotent stem cells (hPSCs) make them a promising source of material for cell transplantation therapy, drug development, and studies of cellular differentiation and development. However, the large numbers of cells necessary for many of thes...
Autores principales: | Garitaonandia, Ibon, Amir, Hadar, Boscolo, Francesca Sesillo, Wambua, Gerald K., Schultheisz, Heather L., Sabatini, Karen, Morey, Robert, Waltz, Shannon, Wang, Yu-Chieh, Tran, Ha, Leonardo, Trevor R., Nazor, Kristopher, Slavin, Ileana, Lynch, Candace, Li, Yingchun, Coleman, Ronald, Gallego Romero, Irene, Altun, Gulsah, Reynolds, David, Dalton, Stephen, Parast, Mana, Loring, Jeanne F., Laurent, Louise C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340884/ https://www.ncbi.nlm.nih.gov/pubmed/25714340 http://dx.doi.org/10.1371/journal.pone.0118307 |
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