Programmed Evolution for Optimization of Orthogonal Metabolic Output in Bacteria

Current use of microbes for metabolic engineering suffers from loss of metabolic output due to natural selection. Rather than combat the evolution of bacterial populations, we chose to embrace what makes biological engineering unique among engineering fields – evolving materials. We harnessed bacter...

Descripción completa

Detalles Bibliográficos
Autores principales: Eckdahl, Todd T., Campbell, A. Malcolm, Heyer, Laurie J., Poet, Jeffrey L., Blauch, David N., Snyder, Nicole L., Atchley, Dustin T., Baker, Erich J., Brown, Micah, Brunner, Elizabeth C., Callen, Sean A., Campbell, Jesse S., Carr, Caleb J., Carr, David R., Chadinha, Spencer A., Chester, Grace I., Chester, Josh, Clarkson, Ben R., Cochran, Kelly E., Doherty, Shannon E., Doyle, Catherine, Dwyer, Sarah, Edlin, Linnea M., Evans, Rebecca A., Fluharty, Taylor, Frederick, Janna, Galeota-Sprung, Jonah, Gammon, Betsy L., Grieshaber, Brandon, Gronniger, Jessica, Gutteridge, Katelyn, Henningsen, Joel, Isom, Bradley, Itell, Hannah L., Keffeler, Erica C., Lantz, Andrew J., Lim, Jonathan N., McGuire, Erin P., Moore, Alexander K., Morton, Jerrad, Nakano, Meredith, Pearson, Sara A., Perkins, Virginia, Parrish, Phoebe, Pierson, Claire E., Polpityaarachchige, Sachith, Quaney, Michael J., Slattery, Abagael, Smith, Kathryn E., Spell, Jackson, Spencer, Morgan, Taye, Telavive, Trueblood, Kamay, Vrana, Caroline J., Whitesides, E. Tucker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340930/
https://www.ncbi.nlm.nih.gov/pubmed/25714374
http://dx.doi.org/10.1371/journal.pone.0118322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340930/
https://www.ncbi.nlm.nih.gov/pubmed/25714374
http://dx.doi.org/10.1371/journal.pone.0118322

Ejemplares similares