Integrative Analysis of Circadian Transcriptome and Metabolic Network Reveals the Role of De Novo Purine Synthesis in Circadian Control of Cell Cycle

Metabolism is the major output of the circadian clock in many organisms. We developed a computational method to integrate both circadian gene expression and metabolic network. Applying this method to zebrafish circadian transcriptome, we have identified large clusters of metabolic genes containing m...

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Detalles Bibliográficos
Autores principales: Li, Ying, Li, Guang, Görling, Benjamin, Luy, Burkhard, Du, Jiulin, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340947/
https://www.ncbi.nlm.nih.gov/pubmed/25714999
http://dx.doi.org/10.1371/journal.pcbi.1004086

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