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Histidine 352 (His(352)) and Tryptophan 355 (Trp(355)) Are Essential for Flax UGT74S1 Glucosylation Activity toward Secoisolariciresinol
Flax secoisolariciresinol diglucoside (SDG) lignan is a natural phytoestrogen for which a positive role in metabolic diseases is emerging. Until recently however, much less was known about SDG and its monoglucoside (SMG) biosynthesis. Lately, flax UGT74S1 was identified and characterized as an enzym...
Autores principales: | Ghose, Kaushik, McCallum, Jason, Sweeney-Nixon, Marva, Fofana, Bourlaye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340967/ https://www.ncbi.nlm.nih.gov/pubmed/25714779 http://dx.doi.org/10.1371/journal.pone.0116248 |
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