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Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy

The effects of tetanus toxin (TeNT) both in the spinal cord, in clinical tetanus, and in the brain, in experimental focal epilepsy, suggest disruption of inhibitory synapses. TeNT is a zinc protease with selectivity for Vesicle Associated Membrane Protein (VAMP; previously synaptobrevin), with a rep...

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Detalles Bibliográficos
Autores principales: Ferecskó, Alex S., Jiruska, Premysl, Foss, Lucy, Powell, Andrew D., Chang, Wei-Chih, Sik, Attila, Jefferys, John G. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341026/
https://www.ncbi.nlm.nih.gov/pubmed/24442865
http://dx.doi.org/10.1007/s00429-013-0697-1