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Substrate recognition and function of the R2TP complex in response to cellular stress

The R2TP complex is a HSP90 co-chaperone, which consists of four subunits: PIH1D1, RPAP3, RUVBL1, and RUVBL2. It is involved in the assembly of large protein or protein–RNA complexes such as RNA polymerase, small nucleolar ribonucleoproteins (snoRNPs), phosphatidylinositol 3 kinase-related kinases (...

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Detalles Bibliográficos
Autores principales: von Morgen, Patrick, Hořejší, Zuzana, Macurek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341119/
https://www.ncbi.nlm.nih.gov/pubmed/25767478
http://dx.doi.org/10.3389/fgene.2015.00069