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Gastrodin blocks neural stem cell differentiation into glial cells mediated by kainic acid★
Kainic acid can simulate excitatory amino acids in vitro. Neural stem cells, isolated from newborn Wistar rats, were cultured in vitro and exposed to 100–4 000 μM kainic acid for 7 days to induce neuronal cell differentiation, causing the number of astrocytes to be significantly increased. Treatment...
Autores principales: | Sun, Guifang, Yuan, Zhihao, Zhang, Boai, Jia, Yanjie, Ji, Yangfei, Ma, Xingrong, Liu, Yu, Liu, Yanru, Wen, Quanqing, Zhao, Yanling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341282/ https://www.ncbi.nlm.nih.gov/pubmed/25722671 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.12.002 |
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