Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★

Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assay...

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Autores principales: Luo, Yanhong, Wei, Yaodong, Wang, Taizhong, Chen, Dongzhu, Lu, Tiansheng, Wu, Ruibo, Si, Keke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Research and Report: Traditional Chinese Medicine and Neuroregeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341283/
https://www.ncbi.nlm.nih.gov/pubmed/25722672
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.12.003
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author Luo, Yanhong
Wei, Yaodong
Wang, Taizhong
Chen, Dongzhu
Lu, Tiansheng
Wu, Ruibo
Si, Keke
author_facet Luo, Yanhong
Wei, Yaodong
Wang, Taizhong
Chen, Dongzhu
Lu, Tiansheng
Wu, Ruibo
Si, Keke
author_sort Luo, Yanhong
collection PubMed
description Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression.
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spelling pubmed-43412832015-02-26 Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★ Luo, Yanhong Wei, Yaodong Wang, Taizhong Chen, Dongzhu Lu, Tiansheng Wu, Ruibo Si, Keke Neural Regen Res Research and Report: Traditional Chinese Medicine and Neuroregeneration Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression. Medknow Publications & Media Pvt Ltd 2012-04-25 /pmc/articles/PMC4341283/ /pubmed/25722672 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.12.003 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research and Report: Traditional Chinese Medicine and Neuroregeneration
Luo, Yanhong
Wei, Yaodong
Wang, Taizhong
Chen, Dongzhu
Lu, Tiansheng
Wu, Ruibo
Si, Keke
Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
title Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
title_full Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
title_fullStr Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
title_full_unstemmed Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
title_short Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
title_sort pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning★
topic Research and Report: Traditional Chinese Medicine and Neuroregeneration
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341283/
https://www.ncbi.nlm.nih.gov/pubmed/25722672
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.12.003
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