TAM macrophages promote growth and metastasis within the cancer ecosystem

Cancer continues to be the major cause of morbidity and death of more than 500,000 people in the US annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and metastasis. As an invasive species in the tumor microenvironment, they provide an ideal the...

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Detalles Bibliográficos
Autores principales: Zarif, Jelani C, Taichman, Russell S, Pienta, Kenneth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341447/
https://www.ncbi.nlm.nih.gov/pubmed/25954596
http://dx.doi.org/10.4161/21624011.2014.941734
Descripción
Sumario:Cancer continues to be the major cause of morbidity and death of more than 500,000 people in the US annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and metastasis. As an invasive species in the tumor microenvironment, they provide an ideal therapeutic target.

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