TAM macrophages promote growth and metastasis within the cancer ecosystem

Cancer continues to be the major cause of morbidity and death of more than 500,000 people in the US annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and metastasis. As an invasive species in the tumor microenvironment, they provide an ideal the...

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Autores principales: Zarif, Jelani C, Taichman, Russell S, Pienta, Kenneth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341447/
https://www.ncbi.nlm.nih.gov/pubmed/25954596
http://dx.doi.org/10.4161/21624011.2014.941734
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author Zarif, Jelani C
Taichman, Russell S
Pienta, Kenneth J
author_facet Zarif, Jelani C
Taichman, Russell S
Pienta, Kenneth J
author_sort Zarif, Jelani C
collection PubMed
description Cancer continues to be the major cause of morbidity and death of more than 500,000 people in the US annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and metastasis. As an invasive species in the tumor microenvironment, they provide an ideal therapeutic target.
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spelling pubmed-43414472015-07-03 TAM macrophages promote growth and metastasis within the cancer ecosystem Zarif, Jelani C Taichman, Russell S Pienta, Kenneth J Oncoimmunology Author's View Cancer continues to be the major cause of morbidity and death of more than 500,000 people in the US annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and metastasis. As an invasive species in the tumor microenvironment, they provide an ideal therapeutic target. Taylor & Francis 2014-07-03 /pmc/articles/PMC4341447/ /pubmed/25954596 http://dx.doi.org/10.4161/21624011.2014.941734 Text en © 2014 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Zarif, Jelani C
Taichman, Russell S
Pienta, Kenneth J
TAM macrophages promote growth and metastasis within the cancer ecosystem
title TAM macrophages promote growth and metastasis within the cancer ecosystem
title_full TAM macrophages promote growth and metastasis within the cancer ecosystem
title_fullStr TAM macrophages promote growth and metastasis within the cancer ecosystem
title_full_unstemmed TAM macrophages promote growth and metastasis within the cancer ecosystem
title_short TAM macrophages promote growth and metastasis within the cancer ecosystem
title_sort tam macrophages promote growth and metastasis within the cancer ecosystem
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341447/
https://www.ncbi.nlm.nih.gov/pubmed/25954596
http://dx.doi.org/10.4161/21624011.2014.941734
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