Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression

Central insulin receptor-mediated signaling is attracting the growing attention of researchers because of rapidly accumulating evidence implicating it in the mechanisms of plasticity, stress response, and neuropsychiatric disorders including depression. Dicholine succinate (DS), a mitochondrial comp...

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Detalles Bibliográficos
Autores principales: Cline, Brandon H., Costa-Nunes, Joao P., Cespuglio, Raymond, Markova, Natalyia, Santos, Ana I., Bukhman, Yury V., Kubatiev, Aslan, Steinbusch, Harry W. M., Lesch, Klaus-Peter, Strekalova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341562/
https://www.ncbi.nlm.nih.gov/pubmed/25767439
http://dx.doi.org/10.3389/fnbeh.2015.00037

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