Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors

Glycoprotein hormones (GPHs) are the most complex molecules with hormonal activity. They exist only in vertebrates but the genes encoding their subunits’ ancestors are found in most vertebrate and invertebrate species although their roles are still unknown. In the present report, we review the avail...

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Detalles Bibliográficos
Autores principales: Cahoreau, Claire, Klett, Danièle, Combarnous, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341566/
https://www.ncbi.nlm.nih.gov/pubmed/25767463
http://dx.doi.org/10.3389/fendo.2015.00026
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author Cahoreau, Claire
Klett, Danièle
Combarnous, Yves
author_facet Cahoreau, Claire
Klett, Danièle
Combarnous, Yves
author_sort Cahoreau, Claire
collection PubMed
description Glycoprotein hormones (GPHs) are the most complex molecules with hormonal activity. They exist only in vertebrates but the genes encoding their subunits’ ancestors are found in most vertebrate and invertebrate species although their roles are still unknown. In the present report, we review the available structural and functional data concerning GPHs and their subunits’ ancestors.
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spelling pubmed-43415662015-03-12 Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors Cahoreau, Claire Klett, Danièle Combarnous, Yves Front Endocrinol (Lausanne) Endocrinology Glycoprotein hormones (GPHs) are the most complex molecules with hormonal activity. They exist only in vertebrates but the genes encoding their subunits’ ancestors are found in most vertebrate and invertebrate species although their roles are still unknown. In the present report, we review the available structural and functional data concerning GPHs and their subunits’ ancestors. Frontiers Media S.A. 2015-02-26 /pmc/articles/PMC4341566/ /pubmed/25767463 http://dx.doi.org/10.3389/fendo.2015.00026 Text en Copyright © 2015 Cahoreau, Klett and Combarnous. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Cahoreau, Claire
Klett, Danièle
Combarnous, Yves
Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors
title Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors
title_full Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors
title_fullStr Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors
title_full_unstemmed Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors
title_short Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors
title_sort structure–function relationships of glycoprotein hormones and their subunits’ ancestors
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341566/
https://www.ncbi.nlm.nih.gov/pubmed/25767463
http://dx.doi.org/10.3389/fendo.2015.00026
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