Protection against Multiple Subtypes of Influenza Viruses by Virus-Like Particle Vaccines Based on a Hemagglutinin Conserved Epitope

We selected the conserved sequence in the stalk region of influenza virus hemagglutinin (HA) trimmer, the long alpha helix (LAH), as the vaccine candidate sequence, and inserted it into the major immunodominant region (MIR) of hepatitis B virus core protein (HBc), and, by using the E. coli expressio...

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Detalles Bibliográficos
Autores principales: Chen, Shaoheng, Zheng, Dan, Li, Changgui, Zhang, Wenjie, Xu, Wenting, Liu, Xueying, Fang, Fang, Chen, Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341857/
https://www.ncbi.nlm.nih.gov/pubmed/25767809
http://dx.doi.org/10.1155/2015/901817

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