Transcriptional Profile of Muscle following Acute Induction of Symptoms in a Mouse Model of Kennedy's Disease/Spinobulbar Muscular Atrophy

BACKGROUND: Kennedy’s disease/Spinobulbar muscular atrophy (KD/SBMA) is a degenerative neuromuscular disease affecting males. This disease is caused by polyglutamine expansion mutations of the androgen receptor (AR) gene. Although KD/SBMA has been traditionally considered a motor neuron disease, eme...

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Detalles Bibliográficos
Autores principales: Halievski, Katherine, Mo, Kaiguo, Westwood, J. Timothy, Monks, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341878/
https://www.ncbi.nlm.nih.gov/pubmed/25719894
http://dx.doi.org/10.1371/journal.pone.0118120

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