Cargando…

Reduction in Subventricular Zone-Derived Olfactory Bulb Neurogenesis in a Rat Model of Huntington’s Disease Is Accompanied by Striatal Invasion of Neuroblasts

Huntington’s disease (HD) is an inherited progressive neurodegenerative disorder caused by an expanded CAG repeat in exon 1 of the huntingtin gene (HTT). The primary neuropathology of HD has been attributed to the preferential degeneration of medium spiny neurons (MSN) in the striatum. Reports on st...

Descripción completa

Detalles Bibliográficos
Autores principales: Kandasamy, Mahesh, Rosskopf, Michael, Wagner, Katrin, Klein, Barbara, Couillard-Despres, Sebastien, Reitsamer, Herbert A., Stephan, Michael, Nguyen, Huu Phuc, Riess, Olaf, Bogdahn, Ulrich, Winkler, Jürgen, von Hörsten, Stephan, Aigner, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342015/
https://www.ncbi.nlm.nih.gov/pubmed/25719447
http://dx.doi.org/10.1371/journal.pone.0116069

Ejemplares similares