Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo

Kif2a is a member of the kinesin-13 microtubule depolymerases, which tightly regulate microtubule dynamics for many cellular processes. We characterized Kif2a depletion in Xenopus animal caps and embryos. Kif2a depletion generates defects in blastopore closure. These defects are rescued by removing...

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Detalles Bibliográficos
Autores principales: Eagleson, Gerald, Pfister, Katherine, Knowlton, Anne L., Skoglund, Paul, Keller, Ray, Stukenberg, P. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342028/
https://www.ncbi.nlm.nih.gov/pubmed/25568341
http://dx.doi.org/10.1091/mbc.E13-12-0721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342028/
https://www.ncbi.nlm.nih.gov/pubmed/25568341
http://dx.doi.org/10.1091/mbc.E13-12-0721

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