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TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation
CD30 (TNFRSF8), a tumor necrosis factor receptor family protein, and CD30 variant (CD30v), a ligand-independent form encoding only the cytoplasmic signaling domain, are concurrently overexpressed in transformed human embryonic stem cells (hESCs) or hESCs cultured in the presence of ascorbate. CD30 a...
Autores principales: | Thakar, Nilay Y., Ovchinnikov, Dmitry A., Hastie, Marcus L., Kobe, Bostjan, Gorman, Jeffrey J., Wolvetang, Ernst J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342033/ https://www.ncbi.nlm.nih.gov/pubmed/25568342 http://dx.doi.org/10.1091/mbc.E14-08-1290 |
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